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2012-2013 Biochemistry Year Long Plan


Science Department

2012-2013 Syllabus

Course Title:         Biochemistry        Section:   E                 Grade:     10-12  

Meeting Times:       Mondays 9:30am-10:55am      Room:     241  

Wednesdays 9:30am-10:55am

Fridays 1:00pm-2:25pm


Instructor Information:                                     
Ms. Raksmey Derival                                          
rderival@innovationcharter.org                            
Extra Help:  Tuesdays 3:00pm - 4:00pm or by appointment

Course Description:
Full year course with lab
Students will learn about biochemicals in the human body at the molecular level, and how they operate to keep the human body functional.  There will be an emphasis on how these molecules and their processes relate to human health and disease. The goal is to understand how the major building blocks of cells and tissues are created and destroyed, how enzymes function, and how cellular energy metabolism is regulated.

Strands:
Experimentation:  (30%)
Science is built upon a foundation of experiments.  Students are assessed on the essential habits of experimentations in a wide variety of contexts:  observing, measuring, recording, analyzing, and forming evidence-based conclusions.
Whenever students are required to collect, analyze, and display data, their work will be graded as part of this strand.  All lab notebook grades will be graded under the experimentation strand.  Projects may also include experimentation strand grades.

Enduring Understanding:  (30%)
Often the most innovative advances in science and technology depend on linking together ideas from more than one field.  Scientists must have deep knowledge and an understanding of how multiple ideas are related.  Enduring understanding will assess students’ ability to work with and extend the ideas presented in class.  Students will be assessed through formal and informal means to capture information on their enduring understanding of a topic.  Assignments that will be graded under the enduring understanding strand include quizzes, homework, research related assignments, and projects.

Modeling:  (20%)
Creating models can be an extremely helpful way to transform concepts from the abstract to the concrete.  Students can build physical models, computer simulations, or create conceptual models/maps to represent processes or principles that exist in the natural world.   Modeling is demonstrated through projects, homework, and assessments.  

Work Habits:  (20%)
Work will be completed in a Punctual manner, students will be Prepared for class, students will be Productive during class, and students will contribute to a Positive work environment.  Demonstration of behavior that promotes the 4 Ps, adhering to safety rules, and coming to class prepared will be graded under the work habits strand.  


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FALL SEMESTER:
Note that the timeline may be subject to change

  • Unit 1:  Introduction to Biochemistry & Lab Safety (Week 1 - Week 5)
    • Origins of life
    • Prokaryotes and eukaryotes
    • 5 Kingdoms, 3 Domains
    • Biomolecules
      • Atomic structure
      • Common elements in biochemistry

  • Safety lab contract

  • Student responsibilities

  • Emergency response protocol

  • MSDS familiarity

  • Lab: Familiarity with basic lab equipment


  • Unit 2:  Water - The solvent of biochemical reactions (Week 6 - Week 8)
                                          Properties of water
                                              Acids, bases, and buffers
                                              Lab: Titration

  • Unit 3:  The Cell’s Intricate Components (Week 9 - Week 13)

    • Organization of Cells

      • Organelles and their functions

      • Possible project:  The Cell Playground

    • Mitosis and Meiosis


  • Unit 4:  Biomolecules (Week 14 - Week 19)

    • Overview of the 4 types:  proteins, lipids, nucleic acids, carbohydrates

    • Proteins

      • Amino acids: the protein building blocks

        • Project Ideas:  BFF’s with an Amino Acid – An Interview Series, Three dimensional structure of proteins

      • Protein purification and characterization

        • Isolation/Separation

        • Electrophoresis
      • Behavior of proteins: enzymes and their control mechanisms
    • Lipids
      • Description
      • Lipids and proteins in biological membranes
      • Project:  Biological Membrane Models



SPRING SEMESTER
:

  • The Genetic Code

    • Nucleic acids: How structure conveys information

    • Biosynthesis of nucleic acids: Replication

    • Transcription: Biosynthesis of RNA

    • Translation: Protein synthesis

    • Class project: Skit-skidaddling with transcription and translation

    • Biotechnology

      • Project:  Research on biotechnology companies in MA

    • Nucleic acid biotechnology techniques

      • Separation

      • Detection

      • Restriction endonucleases

      • Recombinant DNA and cloning

      • Stem cell research

      • Genetic engineering


  • Energy and Metabolism
    • Metabolism’s energy changes and electron transfer
    • Carbohydrates
    • Glycolysis
    • Citric acid cycle
    • Electron transport and oxidative phosphorylation
    • Lipid metabolism
    • Photosynthesis
    • Nitrogen metabolism
    • Project:  Disease Analysis and Cure Proposals
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